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In the summer of 1665, London was gripped by one of the worst epidemics in its history. The outbreak later became known as the Great Plague. Witness hears eye-witness testimony from the time, including an account by famous diarist Samuel Pepys.

(Photo: The angel of death presides over London during the Great Plague of 1664-1666, holding an hourglass in one hand and a spear in the other. Published in The Intelligencer, 26 June 1665. Credit: Hulton Archive/Getty Images)