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There are several thousand brains in Margaret's freezer at work, but she needs more. She's been examining the human brain for over 30 years, in her work on Alzheimer's disease. More recently her work concerns multiple sclerosis, schizophrenia and autism.

So when she wrote to the iPM Listeners' Opinion Poll in the same week that Jeremy Paxman (amongst others) , we wanted to know more.

Professor Margaret Esiri wrote:

'Joining the Organ Donor register does not include an option to donate a brain for research; do you think it should?'

I went to meet Professor Esiri to find out why scientists are in desperate need of our brains.

You can read about appeal for brains and contact her about donating your own after death on the .

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